Contents: Proteomics 8'22

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Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

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Clinical course of 822 children with prenatally detected nephrouropathies.

BACKGROUND AND OBJECTIVES With the advent of fetal screening ultrasonography, the detection of congenital anomalies of the kidney and urinary tract (CAKUT) in utero has permitted early management of these conditions. This study aims to describe the clinical course of a large cohort of patients with prenatally detected nephrouropathies. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS In this ret...

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We illustrate the use of functional system speci cations and their re nement in the development of system components by a simple case study The development includes the modular speci cation re nement and veri cation of system components We start the development with an informal description of the tasks of the case study and then step by step carry out the tasks formally The informal requirement...